RTI uses cookies to offer you the best experience online. By clicking “accept” on this website, you opt in and you agree to the use of cookies. If you would like to know more about how RTI uses cookies and how to manage them please view our Privacy Policy here. You can “opt out” or change your mind by visiting: http://optout.aboutads.info/. Click “accept” to agree.

3 beta-phenyl-2 beta-substituted tropanes - An SAR analysis

Carroll, F., Lewin, A., & Kuhar, MJ. (1998). 3 beta-phenyl-2 beta-substituted tropanes - An SAR analysis. Medicinal Chemistry Research, 8(1-2), 59-65.

Abstract

The 2 beta-carbomethoxy group in cocaine and WIN 35,065-2 can be replaced by a number of other groups with little or no loss in binding affinity to the DAT. Structure-activity relationship (SAR) studies of some 3 beta-aryl-2 beta-substituted tropanes are reviewed in this article.

Publications Info

To contact an RTI author, request a report, or for additional information about publications by our experts, send us your request.