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Search Results

Showing results 21 to 40 of 61.

Article

Calculations of the structure and spectra of the putative transient peroxide intermediates of peroxidases

June 01, 1997
Article

Role of the heme active site and protein environment in structure, spectra, and function of the cytochrome p450s

February 09, 2000
Article

Theoretical study of the ligand-CYP2B4 complexes: Effect of structure on binding free energies and heme spin state

June 01, 2004
Article

Molecular determinants of recognition and activation at GABAA/benzodiazepine receptors

January 01, 2002
Article

Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptor

April 01, 2015
Article

Theoretical investigation of the proton assisted pathway to formation of cytochrome P450 compound I

January 01, 1998
Article

Design, synthesis, and structure–activity relationship studies of novel GPR88 agonists (4-substituted-phenyl)acetamides based on the reversed amide scaffold

December 12, 2023
Article

Chemistry domain of applicability evaluation against existing estrogen receptor high-throughput assay-based activity models

April 17, 2024
Article

Blocking alcoholic steatosis in mice with a peripherally restricted purine antagonist of the type 1 cannabinoid receptor

May 24, 2018
Article

Rational design of cannabinoid type-1 receptor allosteric modulators: Org27569 and PSNCBAM-1 hybrids

July 01, 2021
Article

Oxidation and electronic state dependence of proton transfer in the enzymatic cycle of cytochrome P450eryF

September 20, 2002
Article

Calculation of the electronic structure and spectra of model cytochrome P450 compound I

February 01, 2001
Article

Comparative study of free energies of solvation of phenylimidazole inhibitors of cytochrome P450cam by free energy simulation, AMSOL, and Poisson Boltzmann methods

February 01, 1996
Article

Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2

January 15, 2015
Announcement

RTI International researchers awarded grant funding to explore drugs for chronic pain, cancer

January 08, 2019
Article

Structure-activity relationship development efforts towards peripherally selective analogs of the cannabinoid receptor partial agonist BAY 59-3074

September 02, 2022
Article

Effect of substitution on the aniline moiety of the GPR88 agonist 2-PCCA: Synthesis, structure-activity relationships, and molecular modeling studies

October 19, 2016
Article

Regulation of the apelinergic system and its potential in cardiovascular disease: Peptides and small molecules as tools for discovery

October 22, 2015
Article

High-valent intermediates of heme proteins and model compounds

December 01, 2001
Article

Identifying structural determinants of potency for analogs of apelin-13: Integration of C-terminal truncation with structure-activity

June 01, 2014