Ann Decker

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Diarylureas as Allosteric Modulators of the Cannabinoid CB1 Receptor: Structure-Activity Relationship Studies on 1-(4-Chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1)

Fragmentations of (E)- and (Z)-isomers of 2-methylbuten-1-yl(aryl) iodonium triflates: Competing mechanisms for enol triflate formation

Phenylmorpholines and Analogues Thereof

Development of norepinephrine transporter reuptake inhibition assays using SK-N-BE(2)C cells

Synthesis and pharmacological validation of a novel radioligand for the orphan GPR88 receptor

Vinylogous phenethylamines as neurotransmitter releasers

Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl)}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a selective antagonist for the rat neurotensin receptor type 2

Novel diarylurea based allosteric modulators of the cannabinoid CB1 receptor: Evaluation of importance of 6-pyrrolidinylpyridinyl substitution

Interrogating the Activity of Ligands at Monoamine Transporters in Rat Brain Synaptosomes

Synthesis of a bistetrahydrofuran C17-C32 fragment of the polyether antibiotic ionomycin

Discovery of a potent, selective, and brain-penetrant small molecule that activates the orphan receptor GPR88 and reduces alcohol intake

In vitro and in vivo evaluation of pellotine: A hypnotic lophophora alkaloid

Design, synthesis and pharmacological evaluation of 4-hydroxyphenylglycine and 4-hydroxyphenylglycinol derivatives as GPR88 agonists

Discovery of novel proline-based neuropeptide FF receptor antagonists

Potent and selective tetrahydroisoquinoline kappa opioid receptor antagonists of lead compound (3 R)- N-[1 R)-1-(Cyclohexylmethyl)-2-methylpropyl]-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (CDTic)

Discovery of a novel small molecule agonist scaffold for the APJ receptor

Validation of a high-throughput calcium mobilization assay for the human trace amine-associated receptor 1

Truncated orexin peptides: structure–activity relationship studies

Evaluation of amide bioisosteres leading to 1,2,3-triazole containing compounds as GPR88 agonists: Design, synthesis, and structure-activity relationship studies

Fluorinated phenmetrazine "legal highs" act as substrates for high-affinity monoamine transporters of the SLC6 family