Danni Harris

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Chemistry domain of applicability evaluation against existing estrogen receptor high-throughput assay-based activity models

Design, synthesis, and structure–activity relationship studies of novel GPR88 agonists (4-substituted-phenyl)acetamides based on the reversed amide scaffold

The development of diphenyleneiodonium analogs as GPR3 agonists

Isoquinolone derivatives as lysophosphatidic acid receptor 5 (LPA5) antagonists: Investigation of structure-activity relationships, ADME properties and analgesic effects

Structure-activity relationship development efforts towards peripherally selective analogs of the cannabinoid receptor partial agonist BAY 59-3074

Rational design of cannabinoid type-1 receptor allosteric modulators: Org27569 and PSNCBAM-1 hybrids

Discovery of arylsulfonamides as dual orexin receptor agonists

Therapeutic and prophylactic vaccines to counteract fentanyl use disorders and toxicity

Blocking alcoholic steatosis in mice with a peripherally restricted purine antagonist of the type 1 cannabinoid receptor

Re-sensitizing multidrug resistant bacteria to antibiotics by targeting bacterial response regulators: Characterization and comparison of interactions between 2-aminoimidazoles and the response regulators bfmr fromand qseb fromspp

Discovery of novel proline-based neuropeptide FF receptor antagonists

Development of a peripherally restricted cb1 receptor antagonist for alcoholic steatosis

GPCR activation: Principle component analysis as a diagnostic signature correlated with SAR

Topoisomerase I (Top1): a major target of FL118 for its antitumor efficacy or mainly involved in its side effects of hematopoietic toxicity?

Effect of substitution on the aniline moiety of the GPR88 agonist 2-PCCA: Synthesis, structure-activity relationships, and molecular modeling studies

Regulation of the apelinergic system and its potential in cardiovascular disease: Peptides and small molecules as tools for discovery

The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor

Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptor

Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2

Identifying structural determinants of potency for analogs of apelin-13: Integration of C-terminal truncation with structure-activity