Second-generation antidepressants for preventing seasonal affective disorder in adults

Linda J. Lux; Gerald Gartlehner; Amy M. Greenblatt; Gerald Gartlehner; B Nussbaumer; BN Gaynes; Catherine Forneris; Laura Morgan; A Kaminski-Hartenthaler; Amy M. Greenblatt; J Wipplinger; Linda J. Lux; J Sonis; J Hoffman; Megan G. Van Noord; DR Winkler

Second-generation antidepressants for preventing seasonal affective disorder in adults

Gartlehner, G., Nussbaumer, B., Gaynes, BN., Forneris, CA., Morgan, L., Kaminski-Hartenthaler, A., Greenblatt, A., Wipplinger, J., Lux, L., Sonis, J., Hoffman, J., Van Noord, M., & Winkler, DR. (2015). Second-generation antidepressants for preventing seasonal affective disorder in adults. Cochrane Database of Systematic Reviews, 11, CD011268. https://doi.org/10.1002/14651858.CD011268.pub2

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Abstract

Seasonal affective disorder (SAD) is a seasonal pattern of recurrent major depressive episodes that most commonly occurs during autumn or winter and remits in spring. The prevalence of SAD ranges from 1.5% to 9%, depending on latitude. The predictable seasonal aspect of SAD provides a promising opportunity for prevention. This review - one of four reviews on efficacy and safety of interventions to prevent SAD - focuses on second-generation antidepressants (SGAs).