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NMR-Based Metabolomics Analysis Reproducibly Identifies Unique Subject-Specific Profiles That Change during Peanut Oral Immunotherapy

Vickery, BP., Kulis Jr, MD., Stewart, D., Pathmasiri, W., Hamilton, DK., McRitchie, S., Burgess, J., Sumner, S., & Burks, AW. (2016). NMR-Based Metabolomics Analysis Reproducibly Identifies Unique Subject-Specific Profiles That Change during Peanut Oral Immunotherapy. Journal of Allergy and Clinical Immunology, 137(2 [Supplement]), AB132. https://doi.org/10.1016/j.jaci.2015.12.565

Abstract

Identification of a reliable biomarker of desensitization, and improved understanding of its biology, are major scientific goals in allergy research. We hypothesized that unbiased metabolomics analysis would identify specific signatures associated with allergen desensitization and uncover novel pathways.

10.1016/j.jaci.2015.12.565

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