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People with Alzheimer’s disease and other dementias (PWD) live in various settings that affect the quality of their lives and their health and well-being. This issue brief provides an overview of where PWD live and reviews use of services, quality of care, hospital and emergency department (ED) use, costs of care for PWD, and end-of-life care in various living arrangements. The issue brief concludes with some possible research agendas. In 2017, there were an estimated 5.5 million PWD in the United States (Alzheimer’s Association, 2017). As shown in Table 1, PWD live at home, with caregivers and alone; in residential care settings (RCSs) such as assisted living; and in nursing homes. In addition, PWD live in veteran-specific settings such as State Veteran Homes, prisons, mental hospitals, and unlicensed care homes. Most people with dementia live in the community, but nearly a fifth live in either RCSs or nursing homes. Of people living in the community, most live with others, but a significant portion live alone—indeed, more than the total PWD who live in RCSs or nursing homes.