RTI uses cookies to offer you the best experience online. By clicking “accept” on this website, you opt in and you agree to the use of cookies. If you would like to know more about how RTI uses cookies and how to manage them please view our Privacy Policy here. You can “opt out” or change your mind by visiting: http://optout.aboutads.info/. Click “accept” to agree.
Genetic predisposition to obesity is associated with asthma in US Hispanics/Latinos
Results from the Hispanic community health study/study of Latinos
Guo, Y., Moon, J-Y., Laurie, C. C., North, K. E., Sanchez-Johnsen, L. A., Davis, S., Yu, B., Nyenhuis, S. M., Kaplan, R., Rastogi, D., & Qi, Q. (2018). Genetic predisposition to obesity is associated with asthma in US Hispanics/Latinos: Results from the Hispanic community health study/study of Latinos. Allergy, 73(7), 1547-1550. https://doi.org/10.1111/all.13450
Obesity and asthma are two significant public health issues worldwide. Accumulating evidence has related high body mass index (BMI) and obesity with asthma (1), although a causal role of obesity in the development of asthma remains uncertain. A recent study reported a significant association between genetic predisposition to obesity, estimated by a genetic risk score (GRS) based on 32 BMI-associated variants, and increased risk of childhood asthma in 4,835 European children, supporting a potential causal relationship between obesity and asthma (2). However, it remains unknown whether genetic predisposition to obesity is associated with later-onset asthma which is different from childhood-onset asthma (3). This article is protected by copyright. All rights reserved.
