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Eliciting women's preferences for a vaginal HIV prevention product using a discrete-choice experiment
Browne, E. N., Montgomery, E. T., Mansfield, C., Boeri, M., Mange, B., Beksinska, M., Schwartz, J. L., Clark, M. R., Doncel, G. F., Smit, J., Chirenje, Z. M., & van der Straten, A. (2020). Efficacy is not everything: Eliciting women's preferences for a vaginal HIV prevention product using a discrete-choice experiment. AIDS and Behavior, 24(5), 1443-1451. https://doi.org/10.1007/s10461-019-02715-1
As new female-initiated HIV prevention products enter development, it is crucial to incorporate women's preferences to ensure products will be desired, accepted, and used. A discrete-choice experiment was designed to assess the relative importance of six attributes to stated choice of a vaginally delivered HIV prevention product. Sexually active women in South Africa and Zimbabwe aged 18-30 were recruited from two samples: product-experienced women from a randomized trial of four vaginal placebo forms and product-naive community members. In a tablet-administered survey, 395 women chose between two hypothetical products over eight choice sets. Efficacy was the most important, but there were identifiable preferences among other attributes. Women preferred a product that also prevented pregnancy and caused some wetness (p<0.001). They disliked a daily-use product (p=0.002) and insertion by finger (p=0.002). Although efficacy drove preference, wetness, pregnancy prevention, and dosing regimen were influential to stated choice of a product, and women were willing to trade some level of efficacy to have other more desired attributes.