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"Diagnostic Error”, Chapter 8 in McKean’s “Hospitalist Medicine” represents the first time that diagnostic errors are specifically addressed in a general medicine text. Co-authored by Gordon Schiff MD (Brigham and Women’s Hospital, Boston, MA) and Mark L Graber MD (Senior Fellow, Health Care Quality and Outcomes, RTI International), the chapter emphasizes the frequency of diagnostic error (in the range of 10%), the predisposing system-related and cognitive elements that underlie these errors, and the many factors inherent in modern hospital-based medicine that create challenges to reliable diagnosis. A wide range of interventions are recommended to help make diagnosis in this setting accurate, timely, and efficient.