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Deworming and development: asking the right questions, asking the questions right
Bundy, D. A., Kremer, M., Bleakley, H., Jukes, M., & Miguel, E. (2009). Deworming and development: asking the right questions, asking the questions right. PLoS Neglected Tropical Diseases, 3(1), Article e362. https://doi.org/10.1371/journal.pntd.0000362
Existing evidence indicates that mass school-based deworming is extraordinarily cost-effective once health, educational, and economic outcomes are all taken into account, and it is thus unsurprising that a series of studies from the 1993 World Development Report [18] to the recent Copenhagen Consensus [19] argue that treatment of the most prevalent worm infections is a very high return investment. A review by the Abdul Latif Jameel Poverty Action Lab at the Massachusetts Institute of Technology found that deworming was by far the most cost-effective way to increase primary school participation [20]. These analyses depend in part on the impact of deworming on the biomedical outcomes that are the focus of the Cochrane systematic review [3], but they also depend on the implications for the future development of the individual and society. Future income is a central measure of this development. Because there is strong evidence that obtaining more education leads to higher adult income, the effect of deworming on school participation should be central to any reasonable policy analysis.
We believe that future iterations of the Cochrane review that address the three methodological issues described above and include more detailed coverage of other health and non-health outcomes would be significant contributions for both the biomedical and social science literatures. We agree with Taylor-Robinson and colleagues that more trials would be valuable but we also believe that, based on the current evidence, policymakers who have to make decisions today should treat those infected with soil-transmitted helminths.