RTI uses cookies to offer you the best experience online. By clicking “accept” on this website, you opt in and you agree to the use of cookies. If you would like to know more about how RTI uses cookies and how to manage them please view our Privacy Policy here. You can “opt out” or change your mind by visiting: http://optout.aboutads.info/. Click “accept” to agree.
Developmental Trajectories of Young Girls With Fragile X Syndrome
Hatton, D. D., Wheeler, A., Sideris, J., Sullivan, K., Reichardt, A., Roberts, J., Clark, R., & Bailey, D. (2009). Developmental Trajectories of Young Girls With Fragile X Syndrome. American Journal on Intellectual and Developmental Disabilities, 114(3), 161-171. https://doi.org/10.1352/1944-7558-114.3.161
To describe the early phenotype of girls with full mutation fragile X, we used 54 observations of 15 girls between the ages of 6 months and 9 years to examine developmental trajectories as measured by the Battelle Development Inventory. In this sample, autistic behavior was associated with poorer developmental outcomes, primarily due to interactions of age with autistic behavior, even though autistic behavior, measured continuously, was relatively mild. Although this small sample, ascertained primarily through male relatives with fragile X syndrome, limits generalizability, considerable variability in developmental outcome in young girls was documented. In addition, findings support previous research suggesting that even mild autistic behaviors in girls can be associated with developmental outcomes.
