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Bromine-promoted cyclization of an olefinic alpha-aminonitrile: A practical synthesis of 5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (ADCI)
Gonzalez, J., & Carroll, F. (1996). Bromine-promoted cyclization of an olefinic alpha-aminonitrile: A practical synthesis of 5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (ADCI). Tetrahedron Letters, 37(48), 8655-8658.
The 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine ring system, bearing electron-with drawing substituents at either C5, or C5 and C11, is synthesized via electrophilic cyclization of an olefinic alpha-aminonitrile. Copyright (C) 1996 Elsevier Science Ltd