Biarylpyrazole inverse agonists at the cannabinoid CB1 receptor: Importance of the C-3 carboxamide oxygen/lysine3.28(192) interaction

Herbert H. Seltzman; Michael J. Roche; D Hurst; U Umejiego; D Lynch; Herbert H. Seltzman; Stephen Hyatt; Michael J. Roche; S McAllister; D Fleischer; A Kapur; M Abood; SP Shi; J Jones; D Lewis; P Reggio

Biarylpyrazole inverse agonists at the cannabinoid CB1 receptor: Importance of the C-3 carboxamide oxygen/lysine3.28(192) interaction

Hurst, D., Umejiego, U., Lynch, D., Seltzman, H., Hyatt, S., Roche, M., McAllister, S., Fleischer, D., Kapur, A., Abood, M., Shi, SP., Jones, J., Lewis, D., & Reggio, P. (2006). Biarylpyrazole inverse agonists at the cannabinoid CB1 receptor: Importance of the C-3 carboxamide oxygen/lysine3.28(192) interaction. Journal of Medicinal Chemistry, 49(20), 5969-5987.

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