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Acceptability of the dapivirine vaginal ring in postmenopausal US women
Shapley-Quinn, M. K., Laborde, N., Luecke, E. H., Hoesley, C. J., Salata, R. A., Johnson, S., Nel, A. M., Soto-Torres, L., Chen, B. A., & Van Der Straten, A. (2022). Acceptability of the dapivirine vaginal ring in postmenopausal US women. AIDS Patient Care and STDs, 36(3).
For women in the United States who remain sexually active beyond child-bearing years, susceptibility to HIV infection remains, yet condom use is low. We assessed acceptability of the dapivirine vaginal ring (ring) among 96 postmenopausal US women enrolled in a placebo-controlled multisite phase II trial of the ring, using questionnaires and in-depth interviews. Three quarters of women reported “perfect” adherence (ring never out) over the 3-month trial period. At study exit, the ring was found to be very easy to use by 72%, very comfortable to wear by 65%, and 4% reported it ever interfered with their daily activities. The most common worries among participants at preinitiation had decreased significantly at study exit (e.g., worries about inserting the ring declined from 46% to 6%, discomfort during daily activities from 53% to 3%, ring not staying in place from 48% to 14%, all p
