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SOLUTION

In Vitro Respiratory Modeling and Toxicity Testing

A single source solution for specialized needs in respiratory biology and inhalation toxicology

Expert

David Hines
Expert

Timothy R. Fennell
Expert

Ryan Chartier
Expert

Erin A. Huber
Expert

Sara Maloney Norcross
Article

Epithelial MAPK signaling directs endothelial NRF2 signaling and IL-8 secretion in a tri-culture model of the alveolar-microvascular interface following diesel exhaust particulate (DEP) exposure

March 11, 2024
Article

Exposure effects beyond the epithelial barrier: Transepithelial induction of oxidative stress by diesel exhaust particulates in lung fibroblasts in an organotypic human airway model

September 01, 2020
Article

ERK1/2 and p38 regulate inter-individual variability in ozone-mediated <i>IL</i>-<i>8</i> gene expression in primary human bronchial epithelial cells

June 20, 2018
Article

Ozone responsive gene expression as a model for describing repeat exposure response trajectories and interindividual toxicodynamic variability in vitro

December 28, 2021
Event

American Society for Cellular and Computational Toxicology (ASCCT) Annual Meeting 2024

October 28, 2024
Article

Characterizing the extracellular vesicle proteomic landscape of the human airway using in vitro organotypic multi-cellular models

November 17, 2023
Article

Liquid application dosing alters the physiology of air-liquid interface (ALI) primary human bronchial epithelial cell/lung fibroblast co-cultures and in vitro testing relevant endpoints

January 23, 2024
Event

Webinar | How to Characterize and Validate AI and In Vitro NAMs for Toxicity Testing

September 11, 2024
Article

Minimum information for reporting on the TEER (trans-epithelial/endothelial electrical resistance) assay (MIRTA)

October 04, 2024
Expert

Jonathan Thornburg
Article

New approach methodologies (NAMs) for the in vitro assessment of cleaning products for respiratory irritation: workshop report

October 07, 2024