Greg Sempowski

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Targeted dose delivery of Mycobacterium tuberculosis in mice using silicon antifoaming agent via aerosol exposure system

Centers for Research in Emerging Infectious Diseases (CREID) Coordinating Center

A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice

An epitope-enriched immunogen expands responses to a conserved viral site

Meningococcal detoxified outer membrane vesicle vaccines enhance gonococcal clearance in a murine infection model

Development of mRNA manufacturing for vaccines and therapeutics: mRNA platform requirements and development of a scalable production process to support early phase clinical trials

Cervicovaginal microbiota predicts neisseria gonorrhoeae clinical presentation

A virion-based combination vaccine protects against influenza and SARS-CoV-2 disease in mice

Development of flow cytometry-based assays to assess the ability of antibodies to bind to SARS-CoV-2-infected and spike-transfected cells and mediate NK cell degranulation

STING agonist-containing microparticles improve seasonal influenza vaccine efficacy and durability in ferrets over standard adjuvant

Lymphocyte subset abnormalities in early severe scleroderma favor a Th2 phenotype and are not altered by prior immunosuppressive therapy

An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion

Structural diversity of the SARS-CoV-2 Omicron spike

Early age-related atrophy of cutaneous lymph nodes precipitates an early functional decline in skin immunity in mice with aging

SARS-CoV-2 neutralizing antibodies for COVID-19 prevention and treatment

SARS-CoV-2 reinfection across a spectrum of immunological states

Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion

Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection

Nebulized mRNA-encoded antibodies protect hamsters from SARS-CoV-2 infection

Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine