Search Results
Showing results 21 to 40 of 69.
Article
Dual-acting cholinesterase-human cannabinoid receptor 2 ligands show pronounced neuroprotection in vitro and overadditive and disease-modifying neuroprotective effects in vivo
October 24, 2019
Article
Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as inverse agonists of the CB1 receptor - SAR efforts towards selectivity and peripheralization
August 15, 2019
Patent
Apelin receptor (APJ) agonists and uses thereof
August 13, 2019
Article
Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as peripherally restricted inverse agonists of the CB1 receptor
July 11, 2019
Article
A patent update on cannabinoid receptor 1 antagonists (2015-2018)
April 03, 2019
Patent
Apelin receptor (APJ) agonists and uses thereof
October 16, 2018
Article
Synthesis and pharmacological characterization of functionalized 6-piperazin-1-yl-purines as cannabinoid receptor 1 (CB1) inverse agonists
August 15, 2018
Article
Discovery of a potent, selective, and brain-penetrant small molecule that activates the orphan receptor GPR88 and reduces alcohol intake
August 09, 2018
Article
Development of a peripherally restricted aryl urea based cb1 receptor antagonist for alcoholic steatosis
August 01, 2018
Article
Blocking alcoholic steatosis in mice with a peripherally restricted purine antagonist of the type 1 cannabinoid receptor
May 24, 2018
Article
Development of a peripherally restricted cb1 receptor antagonist for alcoholic steatosis
October 01, 2017
Chapter
Metabolic profiling of CB1 neutral antagonists: (Chapter 9)
July 01, 2017
Article
Development and validation of a high-throughput calcium mobilization assay for the orphan receptor GPR88
March 27, 2017
Patent
Peripherally restricted diphenyl purine derivatives
October 04, 2016
Article
Peripherally selective cannabinoid 1 receptor (CB1R) agonists for the treatment of neuropathic pain
August 25, 2016
Article
Discovery of a novel small molecule agonist scaffold for the APJ receptor
August 15, 2016
Article
Pyrazole antagonists of the CB1 receptor with reduced brain penetration
March 01, 2016
Patent
Peripherally restricted diphenyl purine derivatives
November 17, 2015
Article
Regulation of the apelinergic system and its potential in cardiovascular disease: Peptides and small molecules as tools for discovery
October 22, 2015
Article
Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of the 3-and 4-methyl substituents
October 01, 2015