Bryan Quach

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Alcohol use disorder-associated DNA methylation in the nucleus accumbens and dorsolateral prefrontal cortex

Gene expression differences associated with alcohol use disorder in human brain

Frequent cocaine use is associated with larger HIV latent reservoir size

Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci

Identifying novel gene dysregulation associated with opioid overdose death: A meta-analysis of differential gene expression in human prefrontal cortex

Multi-omic network analysis identifies dysregulated neurobiological pathways in opioid addiction

Trans-ancestry epigenome-wide association meta-analysis of DNA methylation with lifetime cannabis use

Evaluating 17 methods incorporating biological function with GWAS summary statistics to accelerate discovery demonstrates a tradeoff between high sensitivity and high positive predictive value

Network biology algorithms identify bio-logical pathways underlying cigarette smoking behaviors

Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing

Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond

Multi-omic network analysis identifies key neurobiological pathways in opioid addiction (t121)

Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits

Chromatin architecture in addiction circuitry identifies risk genes and biological mechanisms underlying cigarette smoking and alcohol use traits

Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose

Using omics to understand the adverse effects of cocaine use on HIV outcomes

Strategies for cellular deconvolution in human brain RNA sequencing data

Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond

Integration of evidence across human and model organism studies: A meeting report

Epigenome-wide analysis uncovers a blood-based DNA methylation biomarker of lifetime cannabis use