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This report is intended for primary care clinicians: physicians, nurses, nurse practitioners, physician assistants, other allied health professionals, and students. It provides recommendations for clinical practice on preventive interventions -- screening tests, counseling interventions, immunizations, and chemoprophylactic regimens -- for the prevention of more than 80 target conditions. The patients for whom these services are recommended include asymptomatic individuals of all age groups and risk categories. Thus, the subject matter is relevant to all of the major primary care specialties: family practice, internal medicine, obstetrics-gynecology, and pediatrics. The recommendations in each chapter reflect a standardized review of current scientific evidence and include a summary of published clinical research regarding the clinical effectiveness of each preventive service.