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Reagents for screening tests and bioassay of von Willebrand's factor (platelet aggregating factor) in blood plasmas

Brinkhous, KM., & Read, MS. (1979). Reagents for screening tests and bioassay of von Willebrand's factor (platelet aggregating factor) in blood plasmas. (U.S. Patent No. 4145185). http://patft.uspto.gov/netacgi/nph-Parser?patentnumber=4145185

Abstract

Screening tests and bioassay of von Willebrand's factor (platelet aggregating factor) in human and animal blood plasma are effected using a reagent of blood platelets and snake venom having a positive platelet aggregating cofactor effect. The reagent and tests may also suitably employ dried blood platelets. The reagent may comprise dried platelets and either ristocetin or active snake venom as the platelet aggregating cofactor.

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