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Prevalence of SARS-CoV-2 infection among children and adults in 15 US communities, 2021
Justman, J., Skalland, T., Moore, A., Amos, C. I., Marzinke, M. A., Zangeneh, S. Z., Kelley, C. F., Singer, R., Mayer, S., Hirsch-Moverman, Y., Doblecki-Lewis, S., Metzger, D., Barranco, E., Ho, K., Marques, E. T. A., Powers-Fletcher, M., Kissinger, P. J., Farley, J. E., Knowlton, C., ... CoVPN 5002 COMPASS Study Team (2024). Prevalence of SARS-CoV-2 infection among children and adults in 15 US communities, 2021. Emerging Infectious Diseases, 30(2), 245-254. https://doi.org/10.3201/eid3002.230863
During January-August 2021, the Community Prevalence of SARS-CoV-2 Study used time/location sampling to recruit a cross-sectional, population-based cohort to estimate SARS-CoV-2 seroprevalence and nasal swab sample PCR positivity across 15 US communities. Survey-weighted estimates of SARS-CoV-2 infection and vaccine willingness among participants at each site were compared within demographic groups by using linear regression models with inverse variance weighting. Among 22,284 persons >2 months of age and older, median prevalence of infection (prior, active, or both) was 12.9% across sites and similar across age groups. Within each site, average prevalence of infection was 3 percentage points higher for Black than White persons and average vaccine willingness was 10 percentage points lower for Black than White persons and 7 percentage points lower for Black persons than for persons in other racial groups. The higher prevalence of SARS-CoV-2 infection among groups with lower vaccine willingness highlights the disparate effect of COVID-19 and its complications.
