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The invention relates to a method of controlling an invertebrate
pest, comprising contacting the pest with a pest-controlling amount
of an agent having substantial inhibitory activity toward a
phenylethanolamine reuptake transporter as determined by
radioactive octopamine reuptake inhibition assay is disclosed.
Compositions comprising compounds capable of inhibiting the
octopamine reuptake transporter include cocaine analogs. A process
for inhibiting the feeding of an invertebrate pest comprising
contacting said pest with a pest-controlling amount of an agent
having substantial inhibitory activity toward a phenylethanolamine
reuptake transporter as determined by radioactive octopamine
reuptake inhibition assay, with the proviso that said agent is not
cocaine. A process for delaying the maturation of a juvenile
invertebrate by contacting it with an inhibitory amount of a
phenylethanolamine reuptake transporter blocker is also disclosed.
A radioactive phenylethanolamine reuptake inhibition assay for
determining whether a given compound is an inhibitor of octopamine
neuronal transport is also disclosed.