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Metabolism and disposition of alpha-methylstyrene in rats
deCosta, K., Black, SR., Thomas, B., Burgess, J., & Mathews, J. (2001). Metabolism and disposition of alpha-methylstyrene in rats. Drug Metabolism and Disposition, 29(2), 166-171.
α-Methylstyrene (AMS) is a volatile hydrocarbon used primarily in the production of specialty polymers and resins. In the present study, the tissue distribution, metabolism, and excretion of [ 14 C]AMS was investigated in male rats after i.v. administration (11 mg/kg). Over 90% of AMS administered intravenously to rats was excreted in 72 h.
