Kappa opioid receptor ligands

F. Ivy Carroll; S. Mascarella; James B. Thomas; Ivy Carroll; James B. Thomas; S. Wayne Mascarella

Kappa opioid receptor ligands

Carroll, F., Thomas, J., & Mascarella, S. (2005). Kappa opioid receptor ligands. (U.S. Patent No. 6974824). http://patft.uspto.gov/netacgi/nph-Parser?patentnumber=6974824

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Abstract

Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors relative to nor-BNI, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor such as heroin or cocaine addictions.