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Hexahydroindenopyridine compounds having the following formula
and relative stereochemistry ##STR1## where R.sup.1 is C.sub.1-6
alkyl; R.sup.2 is hydrogen or C.sub.1-6 alkyl; R.sup.3 is carboxyl
or a group which is metabolized to a carboxyl group under mammalian
physiological conditions; R.sup.4 is halogen; mixtures of said
compound and acid addition salts thereof exhibit potent
antispermatogenic activity and are useful in a method of inhibiting
spermatogenesis in mammals.