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Early-Life Environmental Exposures and Children’s Health
Foraster, M., Casas, M., Vrijheid, M., & Sunyer, J. (2022). Early-Life Environmental Exposures and Children’s Health. In M. L. Boulton, & R. B. Wallace (Eds.), Maxcy-Rosenau-Last Public Health & Preventive Medicine, 16e (16th ed.). Mcgraw Hill. http://accessmedicine.mhmedical.com/content.aspx?aid=1182673689
The seminal observation by Barker that low birth weight was linked to excess risk of cardiovascular disease (CVD) and mortality in adulthood1 led to the concept of “developmental origins of health and disease” (DOHaD). The idea of “programming” during pregnancy development and risk for chronic diseases occurring late in life was first suggested by nutritional experiments inspired by the concept of early “imprinting” of behavior in birds that has been recognized for centuries.2