Camptothecin analogs as potent inhibitors of topoisomerase I

Monroe E. Wall; Mansukh C. Wani; Monroe E. Wall; Mansukh C. Wani; Allan Nicholas; Govindarajan Manikumar

Camptothecin analogs as potent inhibitors of topoisomerase I

Wall, M., Wani, M., Nicholas, A., & Manikumar, G. (1993). Camptothecin analogs as potent inhibitors of topoisomerase I. (U.S. Patent No. 5244903). http://patft.uspto.gov/netacgi/nph-Parser?patentnumber=5244903

Copy citation

Abstract

A method for synthesizing camptothecin analogs using a novel hydroxyl-containing tricyclic intermediate and the camptothecin analogs produced by the process. The camptothecin analogs are effective inhibitors of topoisomerase.

Recent Publications

Article

The early motor questionnaire facilitates the remote assessment of normative motor development in infancy and toddlerhood

January 01, 2025

Article

Camptothecin analogs as potent inhibitors of topoisomerase I

Abstract

Recent Publications

The early motor questionnaire facilitates the remote assessment of normative motor development in infancy and toddlerhood

Adult vaccination coverage in the United States

Implementing law enforcement-based victim services

Dengue and diabetes comorbidity