RTI uses cookies to offer you the best experience online. By clicking “accept” on this website, you opt in and you agree to the use of cookies. If you would like to know more about how RTI uses cookies and how to manage them please view our Privacy Policy here. You can “opt out” or change your mind by visiting: http://optout.aboutads.info/. Click “accept” to agree.
Body mass index, physical activity and fecundability in a North American preconception cohort study
McKinnon, CJ., Hatch, EE., Rothman, K., Mikkelsen, EM., Wesselink, AK., Hahn, KA., & Wise, LA. (2016). Body mass index, physical activity and fecundability in a North American preconception cohort study. Fertility and Sterility, 106(2), 451-459. https://doi.org/10.1016/j.fertnstert.2016.04.011
OBJECTIVE: To evaluate the association between adiposity, physical activity (PA), and fecundability. DESIGN: Prospective cohort study. SETTING: Not applicable. PATIENT(S): A total of 2,062 female pregnancy planners from the United States and Canada who were enrolled during the preconception period. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Self-reported pregnancy. Fecundability ratios (FRs) and 95% confidence intervals (CIs) were estimated using proportional probabilities models that adjusted for potential confounders. RESULT(S): Relative to body mass index (BMI) 18.5-24 kg/m2, FRs for BMI /=45 kg/m2 were 1.05 (95% CI 0.76-1.46), 1.01 (95% CI 0.89-1.15), 0.98 (95% CI 0.82-1.18), 0.78 (95% CI 0.60-1.02), 0.61 (95% CI 0.42-0.88), and 0.42 (95% CI 0.23-0.76), respectively. Reduced fecundability was observed among women with the largest waist-to-hip ratios (>/=0.85 vs. /=36 vs. /=90 vs. /=5 vs. /=25 kg/m2), fecundability was 27% higher for vigorous PA of >/=5 versus
