Azabicyloalkane phenyl substituted alkane carboxylates, their preparation and use as anticholinergic agents

F. Ivy Carroll; PK Chiang; MM Richard; FN Padilla; Ivy Carroll; Philip Abraham

Azabicyloalkane phenyl substituted alkane carboxylates, their preparation and use as anticholinergic agents

Chiang, PK., Richard, MM., Padilla, FN., Carroll, F., & Abraham, P. (1987). Azabicyloalkane phenyl substituted alkane carboxylates, their preparation and use as anticholinergic agents. (U.S. Patent No. 4713391). http://patft.uspto.gov/netacgi/nph-Parser?patentnumber=4713391

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Abstract

This invention relates to novel compositions, their preparation and the use thereof as anticholinergic agents in the treatment or prophylaxis of organophosphate or nerve gas poisoning in animals. These compositions and pharmaceutical preparations containing them in their free base form and acid addition salts thereof are represented by the formula ##STR1## wherein R represents lower alkyl groups containing 1 to 7 carbon atoms; R.sup.1 represents hydrogen, phenyl, cyclohexyl, and cyclopentyl; and R.sup.2 represents lower alkyl groups containing 1 to 7 carbon atoms, hydroxymethyl, and hydroxyl.

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