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17.alpha.-(substituted-methyl)-17.beta.-hydroxy/esterified hydroxy steroids and pharmaceutical compositions containing them

Cook, C., Tallent, C., Reel, JR., & Wani, M. (1988). 17.alpha.-(substituted-methyl)-17.beta.-hydroxy/esterified hydroxy steroids and pharmaceutical compositions containing them. (U.S. Patent No. 4774236). http://patft.uspto.gov/netacgi/nph-Parser?patentnumber=4774236

Abstract

Steroids of the formula: ##STR1## which are characterized by a 17.alpha.-cyanomethyl, azidomethyl, methoxymethyl, phenylmethyl, or ethynylmethyl substituent and a 17.beta.-hydroxy/esterified hydroxy substituent. The steroids of this invention have glucocorticoid, anti-glucocorticoid, progestational, or anti-progestational activity, depending on the particular structure.

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