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Steroids of the formula: ##STR1## which are characterized by a
17.alpha.-cyanomethyl, azidomethyl, methoxymethyl, phenylmethyl, or
ethynylmethyl substituent and a 17.beta.-hydroxy/esterified hydroxy
substitutent. The steroids of this invention have glucocorticoid,
anti-glucocorticoid, progrestational, or anti-progestational
activity, depending on the particular structure.