Services and Capabilities
Identifying and developing high-throughput screening assays to validate novel drug targets
Our pharmacologists are skilled at elucidating mechanism of action and adapting R&D assays for use with automated liquid handling and incorporation into HTS assays. We have the molecular, biological, and pharmacological expertise to develop and optimize bioassays for HTS campaigns.
We support these campaigns with our proprietary chemical libraries for GPCRs, ion channels, and protein-protein interactions. We also support secondary screens to assess ligand bias and receptor selectivity, as well as hit-to-lead optimization.
Meet the Experts
View All Experts
Navigate to
Shaun D. McCullough
Shaun D. McCullough
Navigate to
Leslimar Ríos-Colón
Leslimar Ríos-Colón
Navigate to
David Hines
David Hines
Navigate to
Elaine Gay
Elaine Gay
Navigate to
Ann Decker
Ann Decker
Navigate to
Rangan (Ronnie) Maitra
Rangan (Ronnie) Maitra
Related Projects
Mapping the Kappa Opioid Receptor Using RTI's JDTic Compound
New insights enable structure-based discovery of new drugs
Read More about Mapping the Kappa Opioid Receptor Using RTI's JDTic Compound
