Modeling and Simulation

Our team of professional modelers uses mathematical modeling and simulation techniques to evaluate biological processes, environmental exposures, social interaction in disease behavior, and associated health outcomes. These techniques help us understand phenomena such as the global spread of disease in situations where the conduct of empirical research is difficult or impossible. Our mathematical models range in complexity from quick laptop applets to supercomputing simulations.

Focus Areas

  • Chronic diseases
  • Infectious and emerging diseases, biothreats
  • Environmental exposure and health risks
  • Cost-effectiveness of medical and public health interventions
  • Epidemic response and containment
  • Resource allocation modeling
  • Forecasting of personnel turnover
  • Predictive models of morbidity and mortality

Capabilities

  • Teams of subject area experts, mathematicians, statisticians, and computer scientists
  • Technical expertise in system dynamics and agent-based modeling
  • Technical expertise in high-performance computing
  • Technical expertise in predictive (forecast) modeling
  • General, topic-specific and custom software
  • Model interpretation to non-technical clients

Projects

  • Cost-effectiveness model for colorectal cancer screening that estimates mortality and morbidity while accounting for differential compliance
  • Epidemiological modeling for chronic illnesses such as diabetes and hepatitis A and C
  • Global model for pandemic influenza examining the worldwide spread of the disease and cost-effectiveness of the containment measures
  • Life cycle inventory of municipal solid waste management alternatives
  • Malaria transmission model
  • Modeling of deforestation policies and land use change
  • Modeling of global and local economic effects of climate change impacts
  • Predictive model of smoking-attributed mortality
  • Resource allocation model for AIDS treatment
  • Simulation models of spread of HIV in networks of injecting drug users
  • State public health laboratory capability and capacity to respond to chemical terrorism

Expert